CD72 antibody (AA 117-359)

Catalog No. ABIN6719589

This anti-CD72 antibody is a Rabbit Polyclonal antibody detecting CD72 in WB and ELISA. Suitable for Human.

Quick Overview for CD72 antibody (AA 117-359) (ABIN6719589)

Target: CD72 (CD72 Molecule (CD72))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD72 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD72 Antibody

Binding Specificity: AA 117-359

Purpose: Anti-CD72 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-CD72 Antibody Picoband® (ABIN6719589). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human CD72 recombinant protein (Position: R117-D359).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Abbas, A.K. and Andrew Licktman, 2003, Cellular and Molecular Immunology, p.512. 2. Kumanogoh, A., Watanabe, C., Lee, I., Wang, X., Shi, W., Araki, H., Hirata, H., Iwahori, K., Uchida, J., Yasui, T., Matsumoto, M., Yoshida, K., Yakura, H., Pan, C., Parnes, J. R., Kikutani, H.Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling. Immunity 13: 621-631, 2000.

Comment:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for CD72

Target: CD72 (CD72 Molecule (CD72))

Alternative Name: CD72

Background:

Synonyms: B-cell differentiation antigen CD72, Lyb-2, CD72, CD72

Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Background: CD72 (Cluster of Differentiation 72), also known in murine biology as Lyb-2, is a protein active in the immune systemof animals. This gene is mapped to 9p13.3. It consists of two identical halves, each of about 39-43 kD, and is a C-type lectin. Its primarily locus of expression is B-cells, where it appears to mediate aspects of B-cell - T-cell interaction. It is a ligand for CD5.

Molecular Weight: 45 kDa

Gene ID: 971

UniProt: P21854

Pathways: BCR Signaling