TIMM17A antibody

Catalog No. ABIN6719637

Product Details anti-TIMM17A Antibody

Target: TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMM17A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: Rabbit IgG polyclonal antibody for TIMM17A detection. Tested with WB, IHC-P, IHC-F, ICC, FCM in Human,Mouse,Rat.

Sequence: LFSMIDCSMV QVRGKED

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for TIMM17A detection. Tested with WB, IHC-P, IHC-F, ICC, FCM in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence of human TIMM17A(LFSMIDCSMVQVRGKED).

Isotype: IgG

Application Details

Application Notes:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Immunohistochemistry(Frozen Section)|0.5-1 μg/mL Immunocytochemistry|0.5-1 μg/mL Flow Cytometry|1-3 μg/1x106 cells

Comment:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for TIMM17A

Target: TIMM17A (Translocase of Inner Mitochondrial Membrane 17 Homolog A (TIMM17A))

Alternative Name: TIMM17A (TIMM17A Products)

Synonyms: TIM17 antibody, TIM17A antibody, Tim17 antibody, Timm17 antibody, 17kDa antibody, mTim17a antibody, translocase of inner mitochondrial membrane 17A antibody, translocase of inner mitochondrial membrane 17a antibody, TIMM17A antibody, Timm17a antibody

Background:

Synonyms: Mitochondrial import inner membrane translocase subunit Tim17-A, Inner membrane preprotein translocase Tim17a, TIMM17A, MIMT17, TIM17, TIM17A, TIMM17

Background: Mitochondrial import inner membrane translocase subunit Tim17-A is an enzyme that in humans is encoded by the TIMM17A gene. It is mapped to 1q32.1. TIM17 is a conserved suppressor of mtDNA instability, and overexpression of TIMM17A can prevent mtDNA loss in a human cellular model of mitochondrial disease.

Gene ID: 10440

UniProt: Q99595