CCL6 antibody (AA 22-116)

Catalog No. ABIN6719644

Product Details anti-CCL6 Antibody

Target: CCL6 (Chemokine (C-C Motif) Ligand 6 (CCL6))

Binding Specificity: AA 22-116

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for CCL6 detection. Tested with WB, IHC-P, ELISA(Cap) in Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for CCL6 detection. Tested with WB, IHC-P, ELISA(Cap) in Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse CCL6 recombinant protein (Position: G22-A116).

Isotype: IgG

Application Details

Application Notes:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL ELISA(Cap)|1-5 μg/mL

Comment:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CCL6

Target: CCL6 (Chemokine (C-C Motif) Ligand 6 (CCL6))

Alternative Name: Ccl6 (CCL6 Products)

Synonyms: MRP-1 antibody, Scya6 antibody, c10 antibody, Abcc1a antibody, Avcc1a antibody, Mrp antibody, Mrp1 antibody, Mrp-1 antibody, Scay6 antibody, chemokine (C-C motif) ligand 6 antibody, ATP binding cassette subfamily C member 1 antibody, Ccl6 antibody, Abcc1 antibody

Background:

Synonyms: C-C motif chemokine 6, Protein C10, Small-inducible cytokine A6, CCL6(22-95), CCL6(23-95), Ccl6, C10, Scya6

Background: Chemokine (C-C motif) ligand 6 (CCL6) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, and can be greatly induced under conditions suitable for myeloid cell differentiation. It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF. Some low levels of gene expression also occur in certain cell lines of myeloid origin (e.g. the immature myeloid cell lines DA3 and 32D cl3, and the macrophage cell line P388D) that can also be greatly induced in culture with GM-CSF. However, in activated T cell lines, expression of CCL6 is greatly reduced.CCL6 can also be induced in the mouse lung by the cytokine interleukin 13. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.

Gene ID: 20305

UniProt: P27784