PTCRA antibody (AA 24-143)

Catalog No. ABIN6719646

Product Details anti-PTCRA Antibody

Target: PTCRA (Pre T-Cell Antigen Receptor alpha (PTCRA))

Binding Specificity: AA 24-143

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTCRA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit IgG polyclonal antibody for PTCRA detection. Tested with WB, Direct ELISA in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for PTCRA detection. Tested with WB, Direct ELISA in Human.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human PTCRA recombinant protein (Position: T24-T143).

Isotype: IgG

Application Details

Application Notes:

Application details: Western blot|0.1-0.5 μg/mL Direct ELISA|0.1-0.5 μg/mL

Comment:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for PTCRA

Target: PTCRA (Pre T-Cell Antigen Receptor alpha (PTCRA))

Alternative Name: PTCRA (PTCRA Products)

Synonyms: gp33 antibody, pT-alpha antibody, pT-alpha-TCR antibody, pT[a] antibody, pTa antibody, pTalpha antibody, PT-ALPHA antibody, PTA antibody, pre T cell antigen receptor alpha antibody, pre T-cell antigen receptor alpha antibody, Ptcra antibody, PTCRA antibody

Background:

Synonyms: Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA

Background: This PTCRA gene is mapped to 6p21.1. The protein encoded by this gene is a single-pass type I membrane protein that is found in immmature but not mature T-cells. Along with TCRB and CD3 complex, the encoded protein forms the pre-T-cell receptor complex, which regulates early T-cell development. Four transcript variants encoding different isoforms have been found for this gene.

Gene ID: 171558

Pathways: Cancer Immune Checkpoints