KBTBD2 antibody

Catalog No. ABIN6719647

Product Details anti-KBTBD2 Antibody

Target: KBTBD2 (Kelch Repeat and BTB (POZ) Domain Containing 2 (KBTBD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KBTBD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Purpose: Rabbit IgG polyclonal antibody for KBTBD2 detection. Tested with WB, ICC/IF in Human,Mouse,Rat.

Sequence: QYDLELDRWS LRQHISERVL WDLGRDFR

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for KBTBD2 detection. Tested with WB, ICC/IF in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence of human KBTBD2(QYDLELDRWSLRQHISERVLWDLGRDFR).

Isotype: IgG

Application Details

Application Notes:

Application details: Western blot|0.1-0.5 μg/mL Immunocytochemistry/Immunofluorescence|2 μg/mL

Comment:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for KBTBD2

Target: KBTBD2 (Kelch Repeat and BTB (POZ) Domain Containing 2 (KBTBD2))

Alternative Name: KBTBD2 (KBTBD2 Products)

Synonyms: BKLHD1 antibody, BC022962 antibody, Bklhd1 antibody, mKIAA1489 antibody, kelch repeat and BTB domain containing 2 antibody, kelch repeat and BTB (POZ) domain containing 2 antibody, Kbtbd2 antibody, KBTBD2 antibody

Background:

Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489

Background: Kelch repeat and BTB domain containing 2(KBTBD2), also known as BTB and kelch domain-containing protein 1, encodes a BTB-Kelch family subunit that p85α-specific recognition for the Cullin3-based E3 ubiqitin ligase complex, which regulates p85α protein ubiquitination and subsequently regulates phosphoinositide-3 kinases (PI3K) signaling. However, the expression profile and functional significance of Kbtbd2 is still largely unknown. The Human Protein Atlas which is an online source shows high Kbtbd2 expression in the spleen and thymus, suggesting that Kbtbd2 might involved in immunization. In addition, Kbtbd2 is related to Src-induced phosphorylation of protein, spermatogonial stem cell activity and insulin sensitivity.

Gene ID: 25948