LDLR antibody (AA 781-860) (Biotin)

Catalog No. ABIN672113

The Rabbit Polyclonal anti-LDLR antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect LDLR in samples from Human, Mouse, Rat, Hamster and Plant.

Quick Overview for LDLR antibody (AA 781-860) (Biotin) (ABIN672113)

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reactivity: Human, Mouse, Rat, Hamster, Plant

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LDLR antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LDLR Antibody (Biotin)

Binding Specificity: AA 781-860

Cross-Reactivity: Hamster, Human, Mouse, Plant, Rat

Cross-Reactivity (Details): Hamster

Predicted Reactivity: Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LDL-R

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Alternative Name: LDL receptor

Background:

Synonyms: FH, FHC, LDLCQ2, Low-density lipoprotein receptor, LDL receptor, LDLR

Background: Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

Gene ID: 3949

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism