CD7 antibody (Alexa Fluor 647)

Catalog No. ABIN6721401

This anti-CD7 antibody is a Mouse Monoclonal antibody detecting CD7 in FACS. Suitable for Human.

Quick Overview for CD7 antibody (Alexa Fluor 647) (ABIN6721401)

Target: CD7

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD7 antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS)

Clone: 124-1D1

Product Details anti-CD7 Antibody (Alexa Fluor 647)

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD7

Target: CD7

Alternative Name: CD7

Background:

Synonyms: T-cell antigen CD7,CD7,GP40,T-cell leukemia antigen,T-cell surface antigen Leu-9,TP41,TP41

Background: CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.

Gene ID: 924

UniProt: P09564

Pathways: Cell-Cell Junction Organization