HLA-ABC antibody (Alexa Fluor 647)
Quick Overview for HLA-ABC antibody (Alexa Fluor 647) (ABIN6722769)
Target
See all HLA-ABC AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Isotype
- IgG2a kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- HLA-ABC
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Alternative Name
- HLA-A,B,C
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Background
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Synonyms: Major Histocompatibility Class I, MHC class I
Background: MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells. They play an important role in cell-mediated immune responses and tumor surveillance.
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Gene ID
- 3105
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UniProt
- P01889
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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