IL3RA antibody (Alexa Fluor 488)

Catalog No. ABIN6722945

The Mouse Monoclonal anti-IL3RA antibody has been validated for FACS. It is suitable to detect IL3RA in samples from Human.

Quick Overview for IL3RA antibody (Alexa Fluor 488) (ABIN6722945)

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL3RA antibody is conjugated to Alexa Fluor 488

Application: Flow Cytometry (FACS)

Clone: 6H6

Product Details anti-IL3RA Antibody (Alexa Fluor 488)

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Alternative Name: CD123

Background:

Synonyms: IL-3Rα, IL-3 Receptor alpha

Background: CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity, when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.

Gene ID: 3563

UniProt: P26951

Pathways: JAK-STAT Signaling