IL7R antibody

Catalog No. ABIN6724132

The Rat Monoclonal anti-IL7R antibody has been validated for FACS, WB, IHC, IP, IF and BR. It is suitable to detect IL7R in samples from Mouse.

Quick Overview for IL7R antibody (ABIN6724132)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL7R antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Blocking Reagent (BR)

Clone: A7R34

Product Details anti-IL7R Antibody

Sterility: 0.2 μm filtered

Endotoxin Level: Endotoxin level is < 2 EU/mg (<0.002EU/μg) as Determined by LAL gel clotting assay.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2. Contains no stabilizers or preservatives.

Preservative: Azide free

Storage: 4 °C

Storage Comment: Store at 2~8°C. Do not freeze.

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: CD127/IL-7RA

Background:

Synonyms: Interleukin-7 receptor subunit alpha,Il7r,IL-7 receptor subunit alpha,IL-7R subunit alpha,IL-7R-alpha,IL-7RA,CD127

Background: CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

Gene ID: 16197

UniProt: P16872

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size