CD31 antibody (Alexa Fluor 647)

Catalog No. ABIN6728253

The Alexa Fluor 647-conjugated Rat Monoclonal anti-CD31 antibody (Clone 390) (ABIN6728253) specifically detects CD31 in FACS. The antibody is reactive with Mouse samples.

Quick Overview for CD31 antibody (Alexa Fluor 647) (ABIN6728253)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD31 antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS)

Clone: 390

Product Details anti-CD31 Antibody (Alexa Fluor 647)

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Alternative Name: CD31

Background:

Synonyms: Pecam, Pecam-1,PECAM-1,CD31

Background: CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.

Gene ID: 18613

UniProt: Q08481

Pathways: Regulation of Actin Filament Polymerization