NCR1 antibody (APC)

Catalog No. ABIN6728289

This Rat Monoclonal antibody specifically detects NCR1 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for NCR1 antibody (APC) (ABIN6728289)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This NCR1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: 29A1-4

Product Details anti-NCR1 Antibody (APC)

Isotype: IgG2a, kappa

Application Details

Application Notes: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Comment:

Matching Isotype Control: APC Rat IgG2a, κ Isotype Control (ABIN7469841)

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Alternative Name: CD335

Background: Ly94,mAR-1,NK-p46,mNKp46,Lymphocyte antigen 94,CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells, it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.

Gene ID: 17086

UniProt: Q8C567

Pathways: Regulation of Leukocyte Mediated Immunity