Lambda-IgLC antibody (PE)
Quick Overview for Lambda-IgLC antibody (PE) (ABIN6731106)
Target
Reactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Purpose
- Anti-Lambda Light Chain PE Antibody
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Characteristics
- The clone HP6054 specifically binds with both soluble and membrane bound human lambda light chain of immunoglobulin but not binds with the kappa light chain or heavy chain. Lambda light chains are primarily expressed on the surface of B cells in lymphoid tissues. Each B cell expresses only one class of light chain kappa or lambda. In serum of a healthy individual, the total kappa to lambda ratio is approximately 3:1 while measuring as intact whole antibodies or 1:1.5 while measuring as free light chains. Various clinical research data claim that any highly divergent ratio of kappa to lambda indicative of neoplasm. HP6054 is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.
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Purification
- Purified
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Purity
- >95 %
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Immunogen
- Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads
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Isotype
- IgG2a, kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- 2-8°C, Conjugated antibodies should never be frozen.
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- Lambda-IgLC (lambda Light Chain (Lambda-IgLC))
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Alternative Name
- Ig Lambda Light Chain
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Gene ID
- 3535
Target
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