TLR5 antibody (AA 701-810)

Catalog No. ABIN673239

This anti-TLR5 antibody is a Rabbit Polyclonal antibody detecting TLR5 in WB, ELISA and IHC (p). Suitable for Human and Mouse. This Primary Antibody has been cited in 4+ publications.

Quick Overview for TLR5 antibody (AA 701-810) (ABIN673239)

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TLR5 Antibody

Binding Specificity: AA 701-810

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse TLR5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TLR5 antibody (ABIN673239)

Li, Yu, Li, Liu, Jiao, Song, Lv, Qin: "Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 5843, (2017) (PubMed).

Sun, Zhan, Liang, Zhang, Song, Han, Hou: "In vivo Toll-like receptor 5 (TLR5) imaging with radiolabeled anti-TLR5 monoclonal antibody in rapamycin-treated mouse allogeneic skin transplantation model." in: Transplant infectious disease : an official journal of the Transplantation Society, Vol. 17, Issue 1, pp. 80-8, (2015) (PubMed).

Hao, Zhang, Liang, Song, Hou: "rFliC prolongs allograft survival in association with the activation of recipient Tregs in a TLR5-dependent manner." in: Cellular & molecular immunology, Vol. 11, Issue 2, pp. 206-14, (2014) (PubMed).

Sun, Yang, Liang, Zhang, Song, Han, Hou: "Non-invasive imaging of allogeneic transplanted skin graft by (131) I-anti-TLR5 mAb." in: Journal of cellular and molecular medicine, (2014) (PubMed).

Target Details for TLR5

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Alternative Name: TLR5

Background:

Synonyms: Toll-like receptor 5, Tlr5

Background: Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Gene ID: 53791

UniProt: Q9JLF7

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades