CDK1 antibody (C-Term)

Catalog No. ABIN6735028

The Mouse Monoclonal anti-CDK1 antibody has been validated for WB, ELISA, IP, IHC (fro) and Func. It is suitable to detect CDK1 in samples from Xenopus laevis.

Quick Overview for CDK1 antibody (C-Term) (ABIN6735028)

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reactivity: Xenopus laevis

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Product Details anti-CDK1 Antibody

Binding Specificity: C-Term

Specificity: Specific for p34cdc2. Does not appear to cross-react with the related p33cdk2 protein. Inhibits the activation of p34cdc2 kinase by cyclin proteins. Species cross-reactivity: Human, rodent, amphibian and chicken.

Cross-Reactivity: Chicken, Human, Rodents

Purification: Protein A Column

Immunogen: Recombinant protein consisting of the carboxy-terminal two-thirds of the Xenopus p34cdc2.

Isotype: IgG2a kappa

Application Details

Application Notes: ELISA (0.1 - 1 µg/mL), Func, IHC-Fr, IP, WB (0.5 - 1 µg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, pH 7.4, 0.1% sodium azide, before the addition of glycerol to 40%

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Avoid repeated freezing and thawing.

Target Details for CDK1

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Alternative Name: CDK1 / CDC2

Background: Standard Gene Symbol: CDK1, Gene Family: Protein Kinase, Gene Subfamily: CDC2/CDK, Synonyms: CDK1, CDC28A, CDC2, CDKN1, Cyclin-dependent kinase 1, p34 protein kinase, p34CDC2, CDC2a, Cell cycle controller CDC2, Cell division protein kinase 1, PSTAIR

Gene ID: 983

UniProt: P06493

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA