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GJB2 antibody (C-Term)

The Rabbit Polyclonal anti-GJB2 antibody has been validated for WB and ELISA. It is suitable to detect GJB2 in samples from Mouse.
Catalog No. ABIN6735217

Quick Overview for GJB2 antibody (C-Term) (ABIN6735217)

Target

See all GJB2 Antibodies
GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Reactivity

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  • 5
  • 2
  • 2
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  • 1
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  • 1
Mouse

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This GJB2 antibody is un-conjugated

Application

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Western Blotting (WB), ELISA
  • Binding Specificity

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    C-Term

    Specificity

    Recognizes mouse connexin 26. Species sequence homology: rat (100 % ), monkey (94 %), human (89 %), sheep, bovine and dog (8 %), rat CX30 (63 %). No significant homology with other connexins.

    Purification

    Immunoaffinity purified

    Immunogen

    A 19 amino acid peptide sequence near the C-terminal, 2nd cytoplasmic domain of the mouse Cx26 (KLH coupled).

    Isotype

    IgG
  • Application Notes

    Approved: ELISA (1:100000), WB (1 - 10 μg/mL)

    Usage: Suitable for use ELISA and Western Blot. Western Blot: 1-10 μg/mL using ECL Recognizes a band of ~25kD in mouse liver. ELISA: 1:100000 using 50-100 ng CX26 control peptide/well.

    Comment

    Target Species of Antibody: Mouse

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Tris,  pH 7.5, 0.2 % BSA, 0.05 % sodium azide, 40 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target

    GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

    Alternative Name

    GJB2 / CX26 / Connexin 26

    Background

    Name/Gene ID: GJB2
    Subfamily: Connexin
    Family: Ion Channel

    Synonyms: GJB2, Connexin 26, Connexin-26, DFNB1A, DFNA3, DFNB1, Gap junction protein beta 2, KID, HID, PPK, NSRD1, CX26, DFNA3A

    Gene ID

    2706

    UniProt

    P29033

    Pathways

    Sensory Perception of Sound, Cell-Cell Junction Organization
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