PTK2B antibody (pTyr402)

Catalog No. ABIN6735486

The Mouse Monoclonal anti-PTK2B antibody has been validated for WB and ELISA. It is suitable to detect PTK2B in samples from Human.

Quick Overview for PTK2B antibody (pTyr402) (ABIN6735486)

Target: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTK2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PTK2B Antibody

Binding Specificity: pTyr402

Specificity: Recognizes human Pyk2 phosphorylated at Tyr402. Species cross-reactivity: Mouse, Rat. Does not cross-react with the non-phosphorylated form of Pyk2/CAKb or with unrelated phosphorylation sites.

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Purification: Gel Filtration Chromatography

Immunogen: Synthetic peptide corresponding to a portion of human Pyk2 (proline-rich tyrosine kinase 2) phosphorylated at Tyr402. Conjugated to KLH.

Isotype: IgG1

Application Details

Application Notes: ELISA (0.05 µg/mL), WB (0.5 µg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.09% sodium azide, G, sucrose, 40% glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.

Target Details for PTK2B

Target: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Alternative Name: PTK2B / PYK2

Background: Standard Gene Symbol: PTK2B, Gene Family: Protein Kinase, Gene Subfamily: Focal Adhesion Kinase, Synonyms: PTK2B, CADTK, CAKB, Cell adhesion kinase beta, FADK 2, FADK2, Focal adhesion kinase 2, FRNK, FAK2, Proline-rich tyrosine kinase 2, Protein-tyrosine kinase 2-beta, Protein kinase B, Protein tyrosine kinase 2 beta, PYK2, RAFTK, CAK-beta, PKB, PTK

Molecular Weight: 116kDa

Gene ID: 2185

UniProt: Q14289

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling