The Mouse Monoclonal anti-CTNNB1 antibody (Clone 1B11) (ABIN6735572) specifically detects CTNNB1 in WB and ELISA.
The antibody is reactive with Human samples.
Recognizes beta-catenin phosphorylated at Tyr654 and -catenin phosphorylated at Tyr654. Detects bands of ~90kD (beta-catenin) and ~70kD (gamma-catenin). Due to sequence homologies of the phospho-epitope surrounding Tyr654, there may be cross-reactions with other proteins (e. g., Annexin A11 at 56kD, desmoplakin at 81kD, TNF-alpha-induced protein 2 at 73kD, ribosomal protein S6 kinase alpha 6 at 90kD). Species cross-reactivity: human, mouse and canine.
Cross-Reactivity
Dog (Canine), Mouse (Murine)
Purification
Gel Filtration Chromatography
Immunogen
Synthetic peptide corresponding to a portion of beta-catenin phosphorylated at Tyr654. Epitope: phosphotyrosine 654 (VATpYAAA).