CREB1 antibody (pSer133)

Catalog No. ABIN6735591

The Rabbit Polyclonal anti-CREB1 antibody has been validated for WB, IHC (p), IP and GS. It is suitable to detect CREB1 in samples from Rat.

Quick Overview for CREB1 antibody (pSer133) (ABIN6735591)

Target: CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Gel Shift (GS)

Product Details anti-CREB1 Antibody

Binding Specificity: pSer133

Specificity: Recognizes p43 phosphorylated CREB. May also recognize p30 and p38kD proteins. The p30 & p38 proteins may be phosphorylated CREM and ATF-1 respectively, since the two proteins share significant homology to the phosphorylated CREB immunizing peptide. Species cross-reactivity: Rat, mouse, human and hamster.

Cross-Reactivity: Hamster, Human, Mouse (Murine)

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Marmoset, Mouse, Rat, Hamster, Elephant, Bat, Bovine, Dog, Rabbit, Pig, Turkey, Chicken, Lizard, Xenopus, Salmon, Stickleback, Pufferfish, Zebrafish (100%).

Purification: Protein A Column

Immunogen: Synthetic phosphopeptide corresponding to residues 123-136 [KRREILSRRP(pS)Y-RK] of rat CREB (cAMP response element binding protein) coupled to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes: GS, IHC-P, IP, WB (1:500)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-glycine, pH 7.4. 15 mM sodium chloride, 0.05% sodium azide, 30% glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Long term: Add glycerol (40-50%) -20°C, Short term: +4°C

Target Details for CREB1

Target: CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))

Alternative Name: CREB1 / CREB

Background: Standard Gene Symbol: CREB1, Gene Family: Transcription factor, Synonyms: CREB1, CREB-1, Transactivator protein, CREB

Gene ID: 1385

UniProt: P16220

Pathways: TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation