Dopamine Receptor d1 antibody (4th Extracellular Domain)

Catalog No. ABIN6735605

This anti-Dopamine Receptor d1 antibody is a Rabbit Polyclonal antibody detecting Dopamine Receptor d1 in WB and ELISA. Suitable for Rat.

Quick Overview for Dopamine Receptor d1 antibody (4th Extracellular Domain) (ABIN6735605)

Target: Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dopamine Receptor d1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Dopamine Receptor d1 Antibody

Binding Specificity: 4th Extracellular Domain

Specificity: Recognizes dopamine receptor D1a. No significant sequence homology with other dopamine receptors (D1B, D2-D5). Species sequence Homology: Human: 88 % (8/9aa), porcine: 77 % (7/9aa).

Purification: Affinity purified

Immunogen: Synthetic peptide 9aa sequence from the rat D1A receptor within the 4th extracellular domain (KLH coupled).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (0.5 - 1 μg/mL), WB (1 - 10 μg/mL)

Usage: Suitable for use in ELISA, Western Blot. Western Blot: 1-10 μg/mL using ECL. Detects 2 proteins of 50 and 75kD in solubilized hippocampal membranes. The 75kD band was not visible in striatum. ~100-400 μg protein/lane should be loaded to visualize the 75kD band. ELISA: 0.5-1 μg/mL. Coat ELISA plates at 1 μg/mL of Control Peptide.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.1 % BSA

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Dopamine Receptor d1

Target: Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

Alternative Name: DRD1 / Dopamine Receptor D1

Background: Name/Gene ID: DRD1
Subfamily: Dopamine
Family: GPCR

Synonyms: DRD1, D(1A) dopamine receptor, D1a dopamine receptor, Dopamine d-1 receptor, Dopamine receptor d1a, DRD1A, DADR, Dopamine d1a receptor, Dopamine receptor D1, Dopamine 1 receptor, Dopamine type 1 receptor, D-1 dopamine receptor, D1 dopamine receptor, D1a receptor, Dopamine D1 receptor

Gene ID: 1812

UniProt: P21728

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity