ABCB6 antibody (AA 401-520)

Catalog No. ABIN673614

The Rabbit Polyclonal anti-ABCB6 antibody (ABIN673614) specifically detects ABCB6 in ELISA, IF (cc), IF (p), IHC (p) and IHC (fro). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ABCB6 antibody (AA 401-520) (ABIN673614)

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB6 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ABCB6 Antibody

Binding Specificity: AA 401-520

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABCB6

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ABCB6

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Alternative Name: ABCB6

Background:

Synonyms: ABC, ABC14, EST45597, ABC 14, ABC-14, ABCB 6, ABCB-6, PRP, UMAT, ABC transporter umat, MTABC3, Mt-ABC transporter 3, umat, Mitochondrial precursor, Mitochondrial ABC transporter 3, Mitochondrial abc protein 3, ATP-binding cassette, sub-family B, member 6, mitochondrial precursor, ATP binding cassette, sub family B MDR/TAP, member 6, P glycoprotein related protein, Abcb6, ABCB6_HUMAN, ATP binding cassette sub family B member 6, mitochondrial precursor, ATP-binding cassette sub-family B member 6, Mitochondrial ABC transporter 3, mitochondrial, Mt ABC transporter 3, P-glycoprotein-related protein, Ubiquitously-expressed mammalian ABC half transporter, UMAT, Ubiquitously expressed mammalian ABC half transporter.

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.

Gene ID: 10058

Pathways: Transition Metal Ion Homeostasis