Claudin 11 antibody (C-Term)

Catalog No. ABIN6736370

This Rabbit Polyclonal antibody specifically detects Claudin 11 in WB, IHC and IHC (p). It exhibits reactivity toward Human, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Pig, Bat and Monkey.

Quick Overview for Claudin 11 antibody (C-Term) (ABIN6736370)

Target: Claudin 11 (CLDN11)

Reactivity: Human, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Pig, Bat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Claudin 11 Antibody

Binding Specificity: C-Term

Brand: IHC-plus™

Specificity: Human CLDN11 / Claudin 11

Predicted Reactivity: Percent identity by BLAST analysis: Dog, Pig (100%) Rat, Chicken (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide from C-Terminus of human CLDN11 (O75508, NP_005593). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Dog, Bovine, Bat, Rabbit, Horse, Pig, Guinea pig (100%), Galago, Elephant, Panda (92%), Marmoset, Mouse, Rat, Opossum, Turkey, Chicken (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for Claudin 11

Target: Claudin 11 (CLDN11)

Alternative Name: CLDN11 / Claudin 11

Background: Name/Gene ID: CLDN11
Family: Claudin

Synonyms: CLDN11, Claudin-11, OSP, OTM, Claudin 11

Gene ID: 5010

NCBI Accession: NP_005593

UniProt: O75508

Pathways: Hepatitis C