Survivin antibody (Cys60) (Alexa Fluor 488)

Catalog No. ABIN6736575

The Alexa Fluor 488-conjugated Rabbit Monoclonal anti-Survivin antibody (ABIN6736575) specifically detects Survivin in IF, ICC and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Survivin antibody (Cys60) (Alexa Fluor 488) (ABIN6736575)

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Survivin antibody is conjugated to Alexa Fluor 488

Application: Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-Survivin Antibody (Alexa Fluor 488)

Binding Specificity: Cys60

Specificity: Detects endogenous levels of total survivin protein. Species cross-reactivity: Human, mouse and rat.

Purification: Purified

Immunogen: Synthetic peptide (KLH-coupled) corresponding to residues surrounding Cys60 of human survivin.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: Flo (1:10), ICC, IF (1:10)

Usage: Suitable for use in Immunofluorescence, Immunocytochemistry and Flow Cytometry. Immunofluorescence (IF-IC): 1:10. Add 10 μL to 5x10^5 cells in 90 μL PBS/0,5 % BSA. Flow Cytometry: 1:10. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, less then 0.1 % sodium azide, 2 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Alternative Name: BIRC5 / Survivin

Background: Name/Gene ID: BIRC5
Family: Apoptosis

Synonyms: BIRC5, API4, Apoptosis inhibitor survivin, Apoptosis inhibitor 4, Survivin, Survivin variant 3 alpha, EPR-1, IAP4

Gene ID: 332

UniProt: O15392

Pathways: Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding