Survivin antibody (Cys60) (Alexa Fluor 488)

Catalog No. ABIN6736575

Product Details anti-Survivin Antibody (Alexa Fluor 488)

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Binding Specificity: Cys60

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Survivin antibody is conjugated to Alexa Fluor 488

Application: Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Specificity: Detects endogenous levels of total survivin protein. Species cross-reactivity: Human, mouse and rat.

Purification: Purified

Immunogen: Synthetic peptide (KLH-coupled) corresponding to residues surrounding Cys60 of human survivin.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: Flo (1:10), ICC, IF (1:10)

Usage: Suitable for use in Immunofluorescence, Immunocytochemistry and Flow Cytometry. Immunofluorescence (IF-IC): 1:10. Add 10 μL to 5x10^5 cells in 90 μL PBS/0,5 % BSA. Flow Cytometry: 1:10. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, less then 0.1 % sodium azide, 2 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Alternative Name: BIRC5 / Survivin (BIRC5 Products)

Background: Name/Gene ID: BIRC5
Family: Apoptosis

Synonyms: BIRC5, API4, Apoptosis inhibitor survivin, Apoptosis inhibitor 4, Survivin, Survivin variant 3 alpha, EPR-1, IAP4

Gene ID: 332

UniProt: O15392

Pathways: Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding