AQP3 antibody (AA 201-292)

Catalog No. ABIN673974

This anti-AQP3 antibody is a Rabbit Polyclonal antibody detecting AQP3 in WB, ELISA, IF (cc), IF (p) and IHC (fro). Suitable for Human, Rat and Mouse. This Primary Antibody has been cited in 1 publication.

Quick Overview for AQP3 antibody (AA 201-292) (ABIN673974)

Target: AQP3 (Aquaporin 3 (Gill Blood Group) (AQP3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AQP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-AQP3 Antibody

Binding Specificity: AA 201-292

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse AQP3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-AQP3 antibody (ABIN673974)

Zhang, Li, Liu, Guang, Yang, Mao, Zhu, Chen, Wang: "The AQP-3 water channel and the ClC-3 chloride channel coordinate the hypotonicity-induced swelling volume in nasopharyngeal carcinoma cells." in: The international journal of biochemistry & cell biology, Vol. 57, pp. 96-107, (2014) (PubMed).

Target Details for AQP3

Target: AQP3 (Aquaporin 3 (Gill Blood Group) (AQP3))

Alternative Name: AQP3

Background:

Synonyms: AQP-2, Aquaporin-3, AQP-3, Aquaglyceroporin-3, Aqp3

Background: Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.

Gene ID: 11828

UniProt: Q8R2N1