LKB1 antibody (AA 317-366)

Catalog No. ABIN6745526

The Rabbit Polyclonal anti-LKB1 antibody has been validated for WB. It is suitable to detect LKB1 in samples from Human, Mouse, Rat, Pig, Monkey, Zebrafish (Danio rerio), Dog, Horse, Hamster and Cow.

Quick Overview for LKB1 antibody (AA 317-366) (ABIN6745526)

Target: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Reactivity: Human, Mouse, Rat, Pig, Monkey, Zebrafish (Danio rerio), Dog, Horse, Hamster, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LKB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LKB1 Antibody

Binding Specificity: AA 317-366

Specificity: Human STK11 / LKB1

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Rat (100%) Chicken, Xenopus (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa317-366 of human STK11 (Q15831, NP_000446). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Galago, Mouse, Rat, Hamster (100%), Opossum, Guinea pig, Zebra finch (92%), Turkey, Chicken, Platypus, Xenopus (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for LKB1

Target: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Alternative Name: STK11 / LKB1

Background: Name/Gene ID: STK11
Subfamily: CAMKL
Family: Protein Kinase

Synonyms: STK11, HLKB1, Peutz-Jeghers syndrome, PJS, Serine/threonine kinase 11, Liver kinase B1, LKB1

Gene ID: 6794

NCBI Accession: NP_000446

UniProt: Q15831

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect