TIM3 antibody (AA 201-250)

Catalog No. ABIN6746552

Product Details anti-TIM3 Antibody

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Binding Specificity: AA 201-250

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIM3 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human HAVCR2 / TIM 3

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Horse (90%) Bovine (83%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa201-250 of human HAVCR2 (Q8TDQ0, NP_116171). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon (100%), Horse (90%), Marmoset (85%), Bovine (83%), Bat (81%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for TIM3

Target: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Alternative Name: HAVCR2 / TIM-3 (TIM 3 Products)

Synonyms: HAVCR2 antibody, MGC140131 antibody, HAVcr-2 antibody, KIM-3 antibody, TIM3 antibody, TIMD-3 antibody, TIMD3 antibody, Tim-3 antibody, TIM-3 antibody, Tim3 antibody, Timd3 antibody, tim3 antibody, hepatitis A virus cellular receptor 2 antibody, HAVCR2 antibody, Havcr2 antibody

Target Type: Virus

Background: Name/Gene ID: HAVCR2

Synonyms: HAVCR2, HAVcr-2, KIM-3, Kidney injury molecule-3, T cell immunoglobulin mucin 3, Tim-3, TIMD3, T-cell membrane protein 3, TIM3, TIMD-3, T cell immunoglobulin mucin-3

Gene ID: 84868

NCBI Accession: NP_116171

UniProt: Q8TDQ0

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints