ADORA1 antibody (C-Term)

Catalog No. ABIN6746718

This anti-ADORA1 antibody is a Rabbit Polyclonal antibody detecting ADORA1 in WB. Suitable for Human, Rat and Pig. This Primary Antibody has been cited in 3+ publications.

Quick Overview for ADORA1 antibody (C-Term) (ABIN6746718)

Target: ADORA1 (Adenosine A1 Receptor (ADORA1))

Reactivity: Human, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADORA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADORA1 Antibody

Binding Specificity: C-Term

Specificity: Human ADORA1 / Adenosine A1 Receptor

Predicted Reactivity: Percent identity by BLAST analysis: Pig (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide from C-Terminus of human ADORA1 (P30542, NP_000665). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (100%), Galago, Marmoset, Horse (92%), Elephant, Pig, Guinea pig (85%), Rabbit (81%), Rat (78%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-ADORA1 antibody (ABIN6746718)

Fallon, Moreau, Croft, Labib, Gu, Fon: "Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 486-91, (2002) (PubMed).

Bowery, Brown: "The cloning of GABA(B) receptors." in: Nature, Vol. 386, Issue 6622, pp. 223-4, (1997) (PubMed).

Dong, OBrien, Fung, Lanahan, Worley, Huganir: "GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors." in: Nature, Vol. 386, Issue 6622, pp. 279-84, (1997) (PubMed).

Target Details for ADORA1

Target: ADORA1 (Adenosine A1 Receptor (ADORA1))

Alternative Name: ADORA1 / Adenosine A1 Receptor

Background: Name/Gene ID: ADORA1
Subfamily: Adenosine
Family: GPCR

Synonyms: ADORA1, A1 adenosine receptor, A1ar, Adenosine A1 receptor, Adenosine receptor A1, ADO-A1 receptor, RDC7

Gene ID: 134

NCBI Accession: NP_000665

UniProt: P30542

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Synaptic Membrane