Adenylosuccinate Lyase antibody (AA 188-237)

Catalog No. ABIN6746728

This Rabbit Polyclonal antibody specifically detects Adenylosuccinate Lyase in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse and Monkey and has been mentioned in 3+ publications.

Quick Overview for Adenylosuccinate Lyase antibody (AA 188-237) (ABIN6746728)

Target: Adenylosuccinate Lyase (ADSL)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenylosuccinate Lyase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Adenylosuccinate Lyase Antibody

Binding Specificity: AA 188-237

Specificity: Human ADSL

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Sheep, Bovine, Rabbit, Pig (92%) Mouse, Rat, Dog, Horse, Guinea pig (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa188-237 of human ADSL (P30566, NP_000017). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%), Sheep, Elephant, Bovine, Rabbit, Pig (92%), Galago, Mouse, Rat, Hamster, Dog, Bat, Horse, Guinea pig (85%), Opossum (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-Adenylosuccinate Lyase antibody (ABIN6746728)

Blumstein, Faundez, Nakatsu, Saito, Ohno, Kelly: "The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 20, pp. 8034-42, (2001) (PubMed).

Zhen, Jiang, Feng, Bright, Peden, Seymour, Novak, Elliott, Gorin, Robinson, Swank: "Abnormal expression and subcellular distribution of subunit proteins of the AP-3 adaptor complex lead to platelet storage pool deficiency in the pearl mouse." in: Blood, Vol. 94, Issue 1, pp. 146-55, (1999) (PubMed).

Ooi, Moreira, DellAngelica, Poy, Wassarman, Bonifacino: "Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet." in: The EMBO journal, Vol. 16, Issue 15, pp. 4508-18, (1997) (PubMed).

Target Details for Adenylosuccinate Lyase

Target: Adenylosuccinate Lyase (ADSL)

Alternative Name: ADSL / Adenylosuccinate Lyase

Background: Name/Gene ID: ADSL

Synonyms: ADSL, Adenylosuccinate lyase, AMPS, ASASE, Adenylosuccinase

Gene ID: 158

NCBI Accession: NP_000017

UniProt: P30566

Pathways: Ribonucleoside Biosynthetic Process