DYRK1A antibody (AA 22-71)

Catalog No. ABIN769026

The Rabbit Polyclonal anti-DYRK1A antibody (ABIN769026) specifically detects DYRK1A in WB, IHC and IHC (p). The antibody is reactive with Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Monkey, Pig and Bat samples.

Quick Overview for DYRK1A antibody (AA 22-71) (ABIN769026)

Target: DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Monkey, Pig, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYRK1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DYRK1A Antibody

Binding Specificity: AA 22-71

Specificity: Mouse DYRK1A

Predicted Reactivity: Percent identity by BLAST analysis: Human, Bovine, Rabbit, Horse, Pig, Guinea pig (100%) Mouse, Dog (92%) Chicken (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa22-71 of mouse Dyrk1a (Q63470, NP_031916). Percent identity by BLAST analysis: Human, Gibbon, Galago, Marmoset, Rat, Elephant, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig (100%), Mouse, Dog, Zebra finch, Platypus (92%), Turkey, Chicken (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for DYRK1A

Target: DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))

Alternative Name: DYRK / DYRK1A

Background: Name/Gene ID: DYRK1A
Subfamily: MNB/DYRK
Family: Protein Kinase

Synonyms: DYRK1A, DYRK1, DYRK, HMNB, HP86, MNB, MNB/DYRK protein kinase, MRD7, MNBH, Serine/threonine kinase MNB, Yak1-related kinase

Gene ID: 1859

NCBI Accession: NP_031916

UniProt: Q13627

Pathways: Mitotic G1-G1/S Phases