EGFR antibody (AA 301-350)
Quick Overview for EGFR antibody (AA 301-350) (ABIN6747988)
Target
See all EGFR AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 301-350
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Specificity
- Human EGFR
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Predicted Reactivity
- Percent identity by BLAST analysis: Human (100%) Horse, Pig, Guinea pig (92%) Bovine (91%) Chicken (90%) Mouse, Rat (84%).
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Purification
- Immunoaffinity purified
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Immunogen
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Synthetic peptide located between aa301-350 of human EGFR (P00533, NP_958439). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Rat, Elephant (100%), Marmoset, Horse, Pig, Opossum, Guinea pig, Platypus (92%), Bovine (91%), Chicken (90%), Galago, Bat (85%), Mouse, Turkey, Zebra finch (84%).
Type of Immunogen: Synthetic peptide
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Distilled water
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS with 2 % sucrose
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Alternative Name
- EGFR
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Background
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Name/Gene ID: EGFR
Subfamily: EGF Receptor
Family: Protein Kinase
Synonyms: EGFR, EGFf receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1 -
Gene ID
- 1956
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NCBI Accession
- NP_958439
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UniProt
- P00533
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Pathways
- NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
Target
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