SNCA antibody

Catalog No. ABIN6757204

The Mouse Monoclonal anti-SNCA antibody is suitable to detect SNCA in samples from Human. It has been validated for WB, IHC, IHC (p) and IP.

Quick Overview for SNCA antibody (ABIN6757204)

Target: SNCA (Synuclein, alpha (SNCA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SNCA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Product Details anti-SNCA Antibody

Specificity: Recognizes Human recombinant alpha-synuclein. Species cross-reactivity: Highly specific for alpha-synuclein and does not react with other synuclein subtypes. Does not react with mouse or rat.

Purification: Protein G purified

Immunogen: Human recombinant alpha-synuclein. MW of Antigen: ~14kD.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: IHC, IHC-P (1:200), IP, WB

Usage: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Immunohistochemistry (formalin/paraffin): 1:200 for 30 min at RT. Note: Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Positive control: Brain.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.2 % BSA, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Alternative Name: SNCA / alpha-Synuclein

Background: Name/Gene ID: SNCA

Synonyms: SNCA, Alpha-synuclein, PARK4, PD1, Synuclein alpha-140, NACP, PARK1

Gene ID: 6622

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity