Transferrin Receptor antibody (N-Term)
Quick Overview for Transferrin Receptor antibody (N-Term) (ABIN334141)
Target
See all Transferrin Receptor (TFRC) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- N-Term
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Specificity
- Reacts with the N-terminus region of the human transferrin receptor. Due to the conserved amino acid sequences of the cytoplasmic tail among species, this antibody is able to cross-react with chicken, mouse and Chinese hamster TR. Cross-reactivity has also been observed with rat adrenal pheochromocytoma (PC-12). Inhibits the internalization of transferrin receptors.
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Purification
- Affinity purified
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Immunogen
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Recombinant human Transferrin Receptor (CD71).
Type of Immunogen: Recombinant protein -
Isotype
- IgG1
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Application Notes
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Approved: ELISA (1 - 5 μg/mL), ICC, IP, WB (1 μg/mL)
Usage: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunocytochemistry, Electron Microscopy. ELISA: 1-5 μg/mL. Western Blot: 1 μg/mL. Immunoprecipitation: 2-5 μg/IP reaction. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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Alternative Name
- CD71 / Transferrin Receptor
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Background
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Name/Gene ID: TFRC
Subfamily: Metallopeptidase M28B
Family: Protease
Synonyms: TFRC, CD71, TFR1, TRFR, TFR, TR, CD71 antigen, p90, T9, Transferrin receptor, Transferrin receptor protein 1 -
Gene ID
- 7037
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UniProt
- P02786
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Pathways
- Transition Metal Ion Homeostasis
Target
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