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Transferrin Receptor antibody (N-Term)

This Mouse Monoclonal antibody specifically detects Transferrin Receptor in WB, ELISA, IP and ICC. It exhibits reactivity toward Human, Mouse, Rat, Chicken and Hamster.
Catalog No. ABIN334141

Quick Overview for Transferrin Receptor antibody (N-Term) (ABIN334141)

Target

See all Transferrin Receptor (TFRC) Antibodies
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity

  • 261
  • 96
  • 36
  • 10
  • 7
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
Human, Mouse, Rat, Chicken, Hamster

Host

  • 154
  • 141
  • 31
  • 4
  • 1
  • 1
  • 1
Mouse

Clonality

  • 218
  • 109
  • 4
Monoclonal

Conjugate

  • 161
  • 32
  • 22
  • 15
  • 10
  • 9
  • 6
  • 6
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  • 6
  • 6
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Transferrin Receptor antibody is un-conjugated

Application

  • 170
  • 165
  • 118
  • 70
  • 62
  • 59
  • 46
  • 22
  • 22
  • 18
  • 12
  • 7
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  • 2
  • 1
  • 1
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Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone

3G291
  • Binding Specificity

    • 36
    • 16
    • 12
    • 10
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term

    Specificity

    Reacts with the N-terminus region of the human transferrin receptor. Due to the conserved amino acid sequences of the cytoplasmic tail among species, this antibody is able to cross-react with chicken, mouse and Chinese hamster TR. Cross-reactivity has also been observed with rat adrenal pheochromocytoma (PC-12). Inhibits the internalization of transferrin receptors.

    Purification

    Affinity purified

    Immunogen

    Recombinant human Transferrin Receptor (CD71).

    Type of Immunogen: Recombinant protein

    Isotype

    IgG1
  • Application Notes

    Approved: ELISA (1 - 5 μg/mL), ICC, IP, WB (1 μg/mL)

    Usage: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunocytochemistry, Electron Microscopy. ELISA: 1-5 μg/mL. Western Blot: 1 μg/mL. Immunoprecipitation: 2-5 μg/IP reaction.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.4, 0.09 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    Alternative Name

    CD71 / Transferrin Receptor

    Background

    Name/Gene ID: TFRC
    Subfamily: Metallopeptidase M28B
    Family: Protease

    Synonyms: TFRC, CD71, TFR1, TRFR, TFR, TR, CD71 antigen, p90, T9, Transferrin receptor, Transferrin receptor protein 1

    Gene ID

    7037

    UniProt

    P02786

    Pathways

    Transition Metal Ion Homeostasis
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