NOS2 antibody (AA 14-100) (Biotin)

Catalog No. ABIN677230

This Rabbit Polyclonal antibody specifically detects NOS2 in WB, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for NOS2 antibody (AA 14-100) (Biotin) (ABIN677230)

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOS2 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NOS2 Antibody (Biotin)

Binding Specificity: AA 14-100

Purpose: iNOS Polyclonal Antibody, Biotin Conjugated

Cross-Reactivity: Rat

Predicted Reactivity: Mouse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse NOS-2

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NOS2

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Alternative Name: iNOS

Background:

Synonyms: iNOS, Nos-2, Nos2a, i-NOS, NOS-II, Nitric oxide synthase, inducible, Inducible NO synthase, Inducible NOS, Macrophage NOS, MAC-NOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2, Nos2, Inosl

Background: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.

Gene ID: 18126

UniProt: P29477

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process