Heme Oxygenase 1, Heme Oxygenase 2 (AA 101-200) antibody (HRP)
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- Target
- Heme Oxygenase 1, Heme Oxygenase 2
- Binding Specificity
- AA 101-200
- Reactivity
- Chicken, Human, Mouse, Pig, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- HRP
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Chicken, Human, Mouse, Pig, Rat
- Predicted Reactivity
- Dog,Cow,Sheep,Horse,Rabbit,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Heme Oxygenase 1
- Isotype
- IgG
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Heme Oxygenase 1, Heme Oxygenase 2
- Background
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Synonyms: HO-1, HSP32, HMOX1D, bK286B1, HMOX1, HO, HO1
Background: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
- Gene ID
- 3162
- UniProt
- P09601
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