ADAM17 antibody (AA 226-473)

Catalog No. ABIN6776494

This anti-ADAM17 antibody is a Mouse Monoclonal antibody detecting ADAM17 in WB. Suitable for Human.

Quick Overview for ADAM17 antibody (AA 226-473) (ABIN6776494)

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADAM17 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADAM17 Antibody

Binding Specificity: AA 226-473

Specificity: The antibody is a mouse monoclonal antibody raised against ADAM17. It has been selected for its ability to recognize ADAM17 in immunohistochemical staining and western blotting.

Purification: Protein A + Protein G affinity chromatography

Immunogen: Recombinant ADAM17 (Lys226-Arg473) expressed in E. coli.

Type of Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: Approved: WB (1:100 - 1:400)

Usage: ELISA 0.05-2 μg/mL, ICC 5-30 μg/mL, WB 0.5-5 μg/mL,

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.02 % sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Aliquot and store at -20°C for up to 1 year. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ADAM17

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Alternative Name: ADAM17 / TACE

Background: Name/Gene ID: ADAM17
Subfamily: Metallopeptidase M12B
Family: Protease

Synonyms: ADAM17, CD156B, CD156b antigen, CSVP, ADAM 17, NISBD, TNF-alpha converting enzyme, TNF-alpha convertase, TNF-alpha-converting enzyme, Snake venom-like protease, TACE

Gene ID: 6868

Pathways: Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus