ARHGEF2 antibody (pSer886)
Quick Overview for ARHGEF2 antibody (pSer886) (ABIN678563)
Target
See all ARHGEF2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer886
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Cross-Reactivity
- Human
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Predicted Reactivity
- Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Arhgef2 around the phosphorylation site of Ser886
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Isotype
- IgG
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Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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- ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))
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Alternative Name
- GEF H1
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Background
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Synonyms: GEF H1phospho S886, Arhgef2Ser886, Lbcl1, Lfc, mKIAA0651, AA408978, ARHG2, ARHGEF 2, ARHGEF-2, ARHGEF2, GEF, GEF H1, GEF-H1, GEFH1, LFP40, MGC95068, P40, Prolerating cell nucleolar antigen p40, Protein GEF-H1, rho/rac guanine nucleotide exchange factor GEF 2, rho/rac guanine nucleotide exchange factor 2, rho/rac guanine nucleotide exchange factor.
Background: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
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Gene ID
- 9181
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Target
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