SIRT1 antibody (AA 236-490) (Biotin)

Catalog No. ABIN2571305

This Rabbit Polyclonal antibody specifically detects SIRT1 in WB. It exhibits reactivity toward Mouse.

Quick Overview for SIRT1 antibody (AA 236-490) (Biotin) (ABIN2571305)

Target: SIRT1 (Sirtuin 1 (SIRT1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT1 antibody is conjugated to Biotin

Application: Western Blotting (WB)

Product Details anti-SIRT1 Antibody (Biotin)

Binding Specificity: AA 236-490

Specificity: Mouse SIRT1 / Sirtuin 1

Purification: Affinity purified

Immunogen: Recombinant SIRT1 (Glu236-Ala490) expressed in E. coli.

Type of Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: Approved: WB (1:100 - 1:400)

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.02 % sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Store frozen product at or below -20°C. Thawed product may be stored for 2-4 weeks at 4°C. For optimal storage, aliquot to smaller portions and store at -20°C to -70°C. Avoid freeze-thaw cycles.

Target Details for SIRT1

Target: SIRT1 (Sirtuin 1 (SIRT1))

Alternative Name: SIRT1 / Sirtuin 1

Background: Name/Gene ID: SIRT1
Family: ADP-Ribosyltransferase

Synonyms: SIRT1, SIR2-like protein 1, SIR2alpha, SIR2L1, Sirtuin 1, Sir2-like 1, Sirtuin type 1, HSIR2, HSIRT1

Gene ID: 23411

Pathways: MAPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling