PRKACA/PRKACB antibody (Cy5)

Catalog No. ABIN680097

The Cy5-conjugated Rabbit Polyclonal anti-PRKACA/PRKACB antibody (ABIN680097) specifically detects PRKACA/PRKACB in WB and IF. The antibody is reactive with Human samples.

Quick Overview for PRKACA/PRKACB antibody (Cy5) (ABIN680097)

Target: PRKACA/PRKACB (PRKACA/B) (Protein Kinase A, alpha/beta (PRKACA/B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKACA/PRKACB antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PRKACA/PRKACB Antibody (Cy5)

Purpose: PKA C alpha + beta Polyclonal Antibody, Cy5 Conjugated

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PKA beta

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PRKACA/PRKACB

Target: PRKACA/PRKACB (PRKACA/B) (Protein Kinase A, alpha/beta (PRKACA/B))

Alternative Name: Pka C Alpha+Beta

Sub Type: Cocktail

Background:

Synonyms: PKA C beta, PKACB, PRKACB, Protein kinase cAMP dependent catalytic beta.

Background: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. PKA beta (catalytic subunit) is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK.

Gene ID: 81491