LAMP2 antibody (AA 301-411)

Catalog No. ABIN680198

The Rabbit Polyclonal anti-LAMP2 antibody has been validated for WB, FACS, ELISA, IHC (fro), IHC (p), IF (p) and IF (cc). It is suitable to detect LAMP2 in samples from Human, Mouse, Rat and Pig. There are 5+ publications available.

Quick Overview for LAMP2 antibody (AA 301-411) (ABIN680198)

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAMP2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-LAMP2 Antibody

Binding Specificity: AA 301-411

Cross-Reactivity: Human, Mouse, Pig, Rat

Predicted Reactivity: Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LAMP2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-LAMP2 antibody (ABIN680198)

Iwao, Ojima, Kobayashi, Kishi, Nara, Esaki, Shimada, Hiraoka, Tanabe, Kanai: "Liver atrophy after percutaneous transhepatic portal embolization occurs in two histological phases: Hepatocellular atrophy followed by apoptosis." in: World journal of hepatology, Vol. 9, Issue 32, pp. 1227-1238, (2017) (PubMed).

Luks, Sacchi, Pollegioni, Dietrich: "Novel insights into renal D-amino acid oxidase accumulation: propiverine changes DAAO localization and peroxisomal size in vivo." in: Archives of toxicology, Vol. 91, Issue 1, pp. 427-437, (2016) (PubMed).

Kameyama, Nakajima, Nishitsuji, Mikawa, Uchimura, Kobayashi, Okuhira, Saito, Sakashita: "Iowa Mutant Apolipoprotein A-I (ApoA-IIowa) Fibrils Target Lysosomes." in: Scientific reports, Vol. 6, pp. 30391, (2016) (PubMed).

Sun, Nie, Wang, Yang, Meng, Xiao, Xiang, Li, Fu, Wang: "Factors that Affect Pancreatic Islet Cell Autophagy in Adult Rats: Evaluation of a Calorie-Restricted Diet and a High-Fat Diet." in: PLoS ONE, Vol. 11, Issue 3, pp. e0151104, (2016) (PubMed).

Zhang, Fu, Sheng, Li, Song, Li, Song, Wang, Chen, Yu, Wei: "Bone marrow CD11b(+)F4/80(+) dendritic cells ameliorate collagen-induced arthritis through modulating the balance between Treg and Th17." in: International immunopharmacology, Vol. 25, Issue 1, pp. 96-105, (2015) (PubMed).

Target Details for LAMP2

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Alternative Name: Lamp2

Background:

Synonyms: LAMPB, CD107b, LAMP-2, LGP110, Lysosome-associated membrane glycoprotein 2, Lysosome-associated membrane protein 2, CD107 antigen-like family member B, LAMP2

Background: Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.

Gene ID: 3920

UniProt: P13473

Pathways: Autophagy