SMO antibody (AA 551-650) (Biotin)

Catalog No. ABIN680910

This anti-SMO antibody is a Rabbit Polyclonal antibody detecting SMO in WB, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for SMO antibody (AA 551-650) (Biotin) (ABIN680910)

Target: SMO (Smoothened Homolog (Drosophila) (SMO))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMO antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SMO Antibody (Biotin)

Binding Specificity: AA 551-650

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Smoothened

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SMO

Target: SMO (Smoothened Homolog (Drosophila) (SMO))

Alternative Name: Smoothened homolog

Background:

Synonyms: Gx, SMOH, FZD11, Smoothened homolog, SMO, Protein Gx

Background: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.

Gene ID: 6608

UniProt: Q99835

Pathways: Hedgehog Signaling