SMO antibody (AA 28-233)

Catalog No. ABIN7169898

Product Details anti-SMO Antibody

Target: SMO (Smoothened Homolog (Drosophila) (SMO))

Binding Specificity: AA 28-233

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMO antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Smoothened homolog protein (28-233AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SMO

Target: SMO (Smoothened Homolog (Drosophila) (SMO))

Alternative Name: SMO (SMO Products)

Synonyms: FZD11 antibody, Gx antibody, SMOH antibody, Smoh antibody, E130215L21Rik antibody, bnb antibody, smoothened antibody, XSmo antibody, smoothened, frizzled class receptor antibody, smoothened, frizzled class receptor L homeolog antibody, SMO antibody, Smo antibody, smo.L antibody, smo antibody

Background:

Background: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.

Aliases: Frizzled family member 11 antibody, FZD11 antibody, Gx antibody, Gx protein antibody, Protein Gx antibody, SMO antibody, SMO_HUMAN antibody, SMOH antibody, Smoothened frizzled family receptor antibody, Smoothened homolog (Drosophila) antibody, Smoothened homolog antibody, Smoothened homolog precursor (SMO) (Gx protein) antibody, Smoothened seven transmembrane spanning receptor antibody

UniProt: Q99835

Pathways: Hedgehog Signaling