PDLIM3 antibody (AA 301-364)

Catalog No. ABIN681823

This Rabbit Polyclonal antibody specifically detects PDLIM3 in ELISA, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PDLIM3 antibody (AA 301-364) (ABIN681823)

Target: PDLIM3 (PDZ and LIM Domain 3 (PDLIM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDLIM3 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PDLIM3 Antibody

Binding Specificity: AA 301-364

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDLIM3

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PDLIM3

Target: PDLIM3 (PDZ and LIM Domain 3 (PDLIM3))

Alternative Name: PDLIM3

Background:

Synonyms: Actinin associated LIM protein, Actinin-associated LIM protein, Alpha actinin 2 associated LIM protein, Alpha-actinin-2-associated LIM protein, DKFZp686L0362, Enigma homolog, PDLI3_HUMAN, PDLIM 3, PDLIM-3, PDLIM3, ALP, PDZ and LIM domain 3, PDZ and LIM domain protein 3.

Background: The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.

Gene ID: 27295

UniProt: Q53GG5