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ARFIP2 antibody (pSer260)

ARFIP2 Reactivity: Human ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN682783
$352.31
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target See all ARFIP2 Antibodies
    ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
    Binding Specificity
    • 15
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer260
    Reactivity
    • 33
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 29
    • 2
    • 2
    Rabbit
    Clonality
    • 32
    • 1
    Polyclonal
    Conjugate
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARFIP2 antibody is un-conjugated
    Application
    • 17
    • 13
    • 13
    • 9
    • 4
    • 4
    • 3
    • 3
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Sheep,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human arfaptin 2 around the phosphorylation site of Ser260
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
    Alternative Name
    arfaptin 2 (ARFIP2 Products)
    Synonyms
    POR1, 2310002N04Rik, POR, Por1, ARFIP2, im:7136059, zgc:112066, ADP ribosylation factor interacting protein 2, ADP-ribosylation factor interacting protein 2, ADP-ribosylation factor interacting protein 2b, ARFIP2, Arfip2, arfip2b
    Background

    ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.

    Subcellular location: Cytoplasm

    Synonyms: ADP ribosylation factor interacting protein 2, Arfaptin 2, ARFIP2, Partner of RAC1, POR1, ARFP2_HUMAN.

    Gene ID
    23647
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