HDAC8 antibody (pSer39) (Biotin)

Catalog No. ABIN684525

This anti-HDAC8 antibody is a Rabbit Polyclonal antibody detecting HDAC8 in ELISA, IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for HDAC8 antibody (pSer39) (Biotin) (ABIN684525)

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC8 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-HDAC8 Antibody (Biotin)

Binding Specificity: pSer39

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HDAC8 around the phosphorylation site of Ser39

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HDAC8

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Alternative Name: HDAC8

Background:

Synonyms: HDAC8 Ser39, HD 8, HD8, HDAC 8, HDACL 1, HDACL1, Histone deacetylase 8, Histone deacetylase like 1, RPD 3, RPD3.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.

Gene ID: 55869

Pathways: Cellular Glucan Metabolic Process