PTAFR antibody (AA 231-342)

Catalog No. ABIN687127

This Rabbit Polyclonal antibody specifically detects PTAFR in ELISA, WB, FACS, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Human, Mouse and Ratand has been mentioned in 1 publication.

Quick Overview for PTAFR antibody (AA 231-342) (ABIN687127)

Target: PTAFR (Platelet-Activating Factor Receptor (PTAFR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTAFR antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PTAFR Antibody

Binding Specificity: AA 231-342

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PAFR

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-PTAFR antibody (ABIN687127)

Hammond, Lu, Gelbard: "Platelet Activating Factor Enhances Synaptic Vesicle Exocytosis Via PKC, Elevated Intracellular Calcium, and Modulation of Synapsin 1 Dynamics and Phosphorylation." in: Frontiers in cellular neuroscience, Vol. 9, pp. 505, (2016) (PubMed).

Target Details for PTAFR

Target: PTAFR (Platelet-Activating Factor Receptor (PTAFR))

Alternative Name: PAFR

Background:

Synonyms: PAFR, Platelet-activating factor receptor, PAF-R, PTAFR

Background: Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system.

Gene ID: 5724

UniProt: P25105

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin