BMPR1A antibody (PE-Cy7)

Catalog No. ABIN687560

The Rabbit Polyclonal anti-BMPR1A antibody has been validated for WB and FACS. It is suitable to detect BMPR1A in samples from Human, Mouse and Rat.

Quick Overview for BMPR1A antibody (PE-Cy7) (ABIN687560)

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMPR1A antibody is conjugated to PE-Cy7

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-BMPR1A Antibody (PE-Cy7)

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BMPR-1A

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BMPR1A

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Alternative Name: BMPR1A/CD292

Background:

Synonyms: ALK3, SKR5, CD292, ACVRLK3, 10q23del, Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, Activin receptor-like kinase 3, ALK-3, Serine/threonine-protein kinase receptor R5, BMPR1A

Background: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.

Molecular Weight: 59kDa

Gene ID: 657

UniProt: P36894

Pathways: Stem Cell Maintenance