IL7R antibody

Catalog No. ABIN6923149

This anti-IL7R antibody is a Mouse Monoclonal antibody detecting IL7R in FACS, IP and Neut. Suitable for Human. This Primary Antibody has been cited in 39+ publications.

Quick Overview for IL7R antibody (ABIN6923149)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL7R antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Neutralization (Neut)

Clone: R34-34

Product Details anti-IL7R Antibody

Purification: Purified

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

References for anti-IL7R antibody (ABIN6923149)

Compeer, Flinsenberg, Boon, Hoekstra, Boes: "Tubulation of endosomal structures in human dendritic cells by Toll-like receptor ligation and lymphocyte contact accompanies antigen cross-presentation." in: The Journal of biological chemistry, Vol. 289, Issue 1, pp. 520-8, (2014) (PubMed).

Faller, McVey, MacPherson: "IL-7 receptor recovery on CD8 T-cells isolated from HIV+ patients is inhibited by the HIV Tat protein." in: PLoS ONE, Vol. 9, Issue 7, pp. e102677, (2014) (PubMed).

Larbi, Mitjavila-Garcia, Flamant, Valogne, Clay, Usunier, lHomme, Féraud, Casal, Gobbo, Divers, Chapel, Turhan, Bennaceur-Griscelli, Haddad: "Generation of multipotent early lymphoid progenitors from human embryonic stem cells." in: Stem cells and development, Vol. 23, Issue 24, pp. 2983-95, (2014) (PubMed).

Lozza, Farinacci, Faé, Bechtle, Stäber, Dorhoi, Bauer, Ganoza, Weber, Kaufmann: "Crosstalk between human DC subsets promotes antibacterial activity and CD8+ T-cell stimulation in response to bacille Calmette-Guérin." in: European journal of immunology, Vol. 44, Issue 1, pp. 80-92, (2014) (PubMed).

Munneke, Björklund, Mjösberg, Garming-Legert, Bernink, Blom, Huisman, van Oers, Spits, Malmberg, Hazenberg: "Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease." in: Blood, Vol. 124, Issue 5, pp. 812-21, (2014) (PubMed).

Péguillet, Milder, Louis, Vincent-Salomon, Dorval, Piperno-Neumann, Scholl, Lantz: "High numbers of differentiated effector CD4 T cells are found in patients with cancer and correlate with clinical response after neoadjuvant therapy of breast cancer." in: Cancer research, Vol. 74, Issue 8, pp. 2204-16, (2014) (PubMed).

Ponchel, Goëb, Parmar, El-Sherbiny, Boissinot, El Jawhari, Burska, Vital, Harrison, Conaghan, Hensor, Emery: "An immunological biomarker to predict MTX response in early RA." in: Annals of the rheumatic diseases, Vol. 73, Issue 11, pp. 2047-53, (2014) (PubMed).

Sereti, Estes, Thompson, Morcock, Fischl, Croughs, Beq, Lafaye de Micheaux, Yao, Ober, Wilson, Natarajan, Imamichi, Boulassel, Lederman, Routy: "Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration." in: PLoS pathogens, Vol. 10, Issue 1, pp. e1003890, (2014) (PubMed).

Yu, Pappu, Ramirez-Carrozzi, Ota, Caplazi, Zhang, Yan, Xu, Lee, Grogan: "TNF superfamily member TL1A elicits type 2 innate lymphoid cells at mucosal barriers." in: Mucosal immunology, Vol. 7, Issue 3, pp. 730-40, (2014) (PubMed).

Bernink, Peters, Munneke, te Velde, Meijer, Weijer, Hreggvidsdottir, Heinsbroek, Legrand, Buskens, Bemelman, Mjösberg, Spits: "Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues." in: Nature immunology, Vol. 14, Issue 3, pp. 221-9, (2013) (PubMed).

Ghazawi, Faller, Sugden, Kakal, MacPherson: "IL-7 downregulates IL-7Rα expression in human CD8 T cells by two independent mechanisms." in: Immunology and cell biology, Vol. 91, Issue 2, pp. 149-58, (2013) (PubMed).

Luckashenak, Wähe, Breit, Brakebusch, Brocker: "Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 1, pp. 27-35, (2012) (PubMed).

Noakes, Vlachava, Kremmyda, Diaper, Miles, Erlewyn-Lajeunesse, Williams, Godfrey, Calder: "Increased intake of oily fish in pregnancy: effects on neonatal immune responses and on clinical outcomes in infants at 6 mo." in: The American journal of clinical nutrition, Vol. 95, Issue 2, pp. 395-404, (2012) (PubMed).

Petrovas, Yamamoto, Gerner, Boswell, Wloka, Smith, Ambrozak, Sandler, Timmer, Sun, Pan, Poholek, Rao, Brenchley, Alam, Tomaras, Roederer, Douek, Seder, Germain, Haddad, Koup: "CD4 T follicular helper cell dynamics during SIV infection." in: The Journal of clinical investigation, Vol. 122, Issue 9, pp. 3281-94, (2012) (PubMed).

Puronen, Thompson, Imamichi, Beq, Hodge, Rehm, Parker, DerSimonian, Brenchley, Sereti: "Decreased interleukin 7 responsiveness of T lymphocytes in patients with idiopathic CD4 lymphopenia." in: The Journal of infectious diseases, Vol. 205, Issue 9, pp. 1382-90, (2012) (PubMed).

Yatim, Benne, Sobhian, Laurent-Chabalier, Deas, Judde, Lelievre, Levy, Benkirane: "NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function." in: Molecular cell, Vol. 48, Issue 3, pp. 445-58, (2012) (PubMed).

Mjösberg, Trifari, Crellin, Peters, van Drunen, Piet, Fokkens, Cupedo, Spits: "Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161." in: Nature immunology, Vol. 12, Issue 11, pp. 1055-62, (2011) (PubMed).

Pankewycz, Leca, Kohli, Wallace, Said, Feng, Alnimri, Patel, Laftavi: "Low-dose rabbit antithymocyte globulin induction therapy results in prolonged selective lymphocyte depletion irrespective of maintenance immunosuppression." in: Transplantation proceedings, Vol. 43, Issue 2, pp. 462-5, (2011) (PubMed).

Young, Angel: "HIV infection of thymocytes inhibits IL-7 activity without altering CD127 expression." in: Retrovirology, Vol. 8, pp. 72, (2011) (PubMed).

Crawley, Faucher, Angel: "Soluble IL-7R alpha (sCD127) inhibits IL-7 activity and is increased in HIV infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 9, pp. 4679-87, (2010) (PubMed).

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: CD127 / IL7R

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size