ABCC1 antibody
Quick Overview for ABCC1 antibody (ABIN6936330)
Target
See all ABCC1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.
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Cross-Reactivity (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant full-length human ABCC1 protein
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Isotype
- IgG1 kappa
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Application Notes
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Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: A549 cells. Colon, Endometrium, Ovary. Testis or Tonsil.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Preservative
- Azide free
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Storage
- -20 °C,-80 °C
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Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Expiry Date
- 24 months
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- ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))
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Alternative Name
- ABCC1
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Background
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ABC29, ABCC1, ATP binding cassette sub family C (CFTR/MRP) member 1, ATP-binding cassette sub-family C member 1, GSX, Leukotriene C(4) transporter, LTC4 transporter, Multidrug resistance-associated protein 1 (MRP1),MRP1 / ABCC1 (Multidrug Resistance Related Protein 1)
Cellular localisation: Cytoplasmic and Cell Surface -
Molecular Weight
- 190kDa
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Gene ID
- 4363, 391464
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UniProt
- P33527
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Pathways
- SARS-CoV-2 Protein Interactome
Target
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