BARX1 antibody

Catalog No. ABIN6936464

This Mouse Monoclonal antibody specifically detects BARX1 in IHC (f). It exhibits reactivity toward Human.

Quick Overview for BARX1 antibody (ABIN6936464)

Target: BARX1 (BARX Homeobox 1 (BARX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BARX1 antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: BARX1-2760

Product Details anti-BARX1 Antibody

Specificity: BarX1 is a member of the Bar subclass of homeobox transcription factors. Studies of the Mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. Down-regulation of Barx1 promotes HCC migration, invasion and metastasis, whereas up-regulation of Barx1 inhibits HCC migration, invasion and metastasis. The loss of Barx1 expression represents a prognostic biomarker in human HCC.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human BARX1 protein.

Isotype: IgG kappa

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HepG2 cell lysate. Human pancreas.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for BARX1

Target: BARX1 (BARX Homeobox 1 (BARX1))

Alternative Name: BARX1

Background: BarH like homeobox 1, BarX 1, BARX homeobox 1, Homeobox protein BarH like 1,BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma)
Cellular localisation: Nuclear.

Molecular Weight: 24kDa

Gene ID: 56033, 164960

Pathways: Sensory Perception of Sound