Clathrin Heavy Chain (CLTC) antibody

Catalog No. ABIN6937004

This Mouse Monoclonal antibody specifically detects Clathrin Heavy Chain in IF. It exhibits reactivity toward Human, Mouse, Rat, Cow, Pig, Dog, Xenopus laevis, Avian and Green Monkey.

Quick Overview for Clathrin Heavy Chain (CLTC) antibody (ABIN6937004)

Target: Clathrin Heavy Chain (CLTC)

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Xenopus laevis, Avian, Green Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunofluorescence (IF)

Clone: CHC-1432

Product Details

Purpose: Clathrin, Heavy Chain Antibody

Specificity: Recognizes protein of 192 kDa, which is identified as Clathrin Heavy Chain. Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain-binding site. The proximal segment of the Clathrin HC protein is essential for interactions between Clathrin heavy chains and light chains, which result in the formation of the triskelion structure.

Cross-Reactivity (Details): Mouse. Rat. Cow. Dog. Human. Pig. Xenopus laevis. Bird. African green monkey.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human Clathrin Heavy Chain protein

Isotype: IgG1, kappa

Application Details

Application Notes:

Known_Application: Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Placenta or Prostate Carcinoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details

Target: Clathrin Heavy Chain (CLTC)

Alternative Name: CLTC

Background:

Clathrin heavy chain, Clathrin heavy chain 1, Clathrin heavy chain 2, Clathrin heavy chain on chromosome 17 (CHC17 or CHC-17), CLH22, CLTC, CLTCL, CLTCL1, CLTCL2, CLTD

HeLa cells. Placenta or Prostate Carcinoma.

Molecular Weight: 192kDa

Gene ID: 1213, 491351

UniProt: P53675, Q00610